Cholestatic jaundice following carbimazole therapy in an elderly thyrotoxic patient.

نویسندگان

  • Hasan Haboubi
  • Dylan Harris
  • Nadim Haboubi
چکیده

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Acute cholestatic hepatitis along with agranulocytosis: a rare side effect of carbimazole.

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Cholestatic jaundice caused by sequential carbimazole and propylthiouracil treatment for thyrotoxicosis.

A 36-year-old Chinese man presented to the Queen Mary Hospital in August 1999 with a 2-week history of jaundice due to propylthiouracil treatment for thyrotoxicosis. He had previously received carbimazole but had developed an urticarial skin rash after 2 weeks of treatment. The patient developed liver failure and fulminant pneumonitis shortly after hospital admission. Despite receiving treatmen...

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Thyrotoxic periodic paralysis (TPP) is a potentially lethal complication of hyperthyroidism characterized by recurrent muscle weakness and hypokalemia. It has been commonly reported in non-Asian populations. Four cases were reported in Saudis so far, and one had a life-threatening arrhythmia. We describe an additional case of a 28-year-old apparently healthy Saudi male patient, who presented wi...

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عنوان ژورنال:
  • Age and ageing

دوره 35 3  شماره 

صفحات  -

تاریخ انتشار 2006